According to stats from the British Retail Consortium, October's town centre vacancy rate hit a 15 month, since July 2011, high at 11.3 per cent (including High Streets and shopping centres).
The BRC began its vacancy monitor in July 2011.
Split down, Northern Ireland fared worst with a 20 per cent rate, followed by Wales at 15.1 per cent and 'the North and Yorkshire' at 14.6 per cent.
In terms of footfall, the three months to October was 0.4 per cent lower than a year ago, but better than the 3.3 per cent fall in the previous quarter. Footfall increased on the High Street in August, driven by the Olympics, the BRC said.
"This new high in empty shop numbers really sets alarm bells ringing," Stephen Robertson, British Retail Consortium Director General. "It's the worst vacancy rate since the survey began in July 2011 and confirms that financial challenges for both customers and retailers are far from over.
"Many retailers are battling stagnating sales and rising costs, and next year's threatened business rates increase can only make matters worse. If the Government wants to breathe life back into our town centres and ensure the retail industry can play its full role in job creation it needs to freeze rates in 2013.
"It's a little more cheering to see footfall suffering less than the previous quarter but shopper numbers were still no better than a year ago. The figures follow a similar pattern to our retail sales monitoring. September's cold snap drew the crowds stocking up on warmer clothing. But, while the Olympics appears to have brought people out onto high streets, that didn't translate into a surge in spending."
Springboard CEO Steve Booth added: "There is no doubt that October had the most detrimental impact on retail footfall over the past quarter.
"Traditionally October is a difficult month for retailers, as school holidays are over and winter weather sets in, however the year-on-year drop in high street footfall this October was significantly better than the drop a year earlier. Furthermore, the quarterly figure has recovered significantly from the -5.5 per cent decline reported in high streets during the previous quarter, when the UK experienced unseasonably wet weather. Though the pace has slowed, the continued decline in footfall could be a factor leading to the 0.4 percentage point increase in vacancy rates. Temporary lets over the festive season may positively affect this figure in November and December and the awareness of increasing vacancy rates has encouraged landlords to become more flexible to try and alleviate this issue, as the heavy rate burden is an ongoing concern for retailers."