Walthamstow's Racer Rosa was ram raided last night and the thieves stole three highly-distinctive bicycles.
The high-end store has bikes made for it in Italy, and has clients such as the former long-jumper and now TV presenter Jonathan Edwards.
In a tweet, the store's owners said: "Ram-raided last night - display bikes and wheels were stolen - please share this and let us know if you see any on sale."
The bikes stolen include a blue Lombardi Corsa road bike, an orange Lombardi Pista track bike, and a blue Lombardi track bike.
"This is a heavy hit for us but we'll be back on our feet very soon," said a store tweet responding to Walthamstow MP Stella Creasy's comment that the "fab" business had been attacked and needed help.