CTC chief executive Gordon Seabright will be leaving CTC at the end of May. He is to become director of the Eden Project in Cornwall.
"In his two year tenure Gordon has had a big impact on CTC," said David Cox, CTC Chair of Council.
"We extend out thanks for all Gordon had done for both CTC and for cycling and wish him well in his future career."
Carol McKinley, CTC's operations director, will act as interim chief executive following Seabright's departure.